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New Study: CBD Successfully Treats Psychosis

Man Laying on Psychiatrists Couch, Credit: Stock Photography


Of the nearly 4 million victims who suffer from the disease, it’s estimated that nearly 50% of them will receive no treatment. This is due in large part to the extremely high expense of medications, as well as a lack of health care availability to a majority of sufferers. The numbers are staggering, but what if there was another, more cost-effective and even all-natural option? That is the question researchers at King’s College London asked and their results are exciting; cannabidiol or CBD reduces the brain activity linked to hallucinations, delusions and other forms of psychosis, research has found.

New Study: CBD Successfully Treats Psychosis

Man Sitting on Psychiatrists Couch, Credit: Stock Photography
Man Sitting on Psychiatrists Couch

While not as common of a condition as arthritis or chronic pain, psychosis still afflicts 4 million people per year, and frighteningly, half of those diagnosed will go untreated.

Psychosis and Schizophrenia

Of the nearly 4 million victims who suffer from the disease, it’s estimated that nearly 50% of them will receive no treatment. This is due in large part to the extremely high expense of medications, as well as a lack of healthcare availability to a majority of sufferers. Likewise, though, this is also why cannabis (and specifically CBD) is becoming a popular treatment option – it’s available to everyone from a relatively manageable price.

Here are some other statistics involving the prevalence of psychosis across the U.S:

  • It is one of the leading causes of disability in America
  • Roughly 75% of victims develop the illness between the ages of 16 and 25
  • Its onset is at least partially genetic
  • In order to receive an official schizophrenia diagnosis, individuals must show consistent symptoms for a minimum of six months
  • According to research, roughly 1 out of 4 people with schizophrenia recover completely, while 2 out of 4 improve over a 10-year period and 1 out of 4 do not improve at all
  • Estimated annual economic costs of between $32.5 and $65 billion are attributed to the treatment of schizophrenia and other forms of psychosis
  • Between 33% and 50% of all homeless adults have some sort of psychosis

CBD for Psychosis and Schizophrenia: An Update on New Studies

Researchers Complete Scientific Study, Credit: Stock Photography
Researchers Complete Scientific Study

Is There An All-Natural Treatment Option?

The numbers are staggering, but what if there was another, more cost-effective, and even all-natural option? That is exactly the question that the researchers at King’s College London were asking in their exciting new study.

A cannabis extract could help treat symptoms of psychosis even though the mental health condition has been linked to long-term recreational use of the drug, UK researchers have found.

The King’s study found that a single dose of CBD could significantly reduce the abnormal brain activity that causes these effects.

Cannabis extract can help treat psychosis, study suggests

What is CBD?

What exactly is this exciting new compound under study? According to the National Institutes of Health:

CBD is one of more than 80 active cannabinoid chemicals in the marijuana plant. Unlike the main psychoactive cannabinoid in marijuana, tetrahydrocannabinol (THC), CBD does not produce euphoria or intoxication. Cannabinoids have their effect mainly by interacting with specific receptors on cells in the brain and body: the CB1 receptor, found on neurons and glial cells in various parts of the brain, and the CB2 receptor, found mainly in the body’s immune system. The euphoric effects of THC are caused by its activation of CB1 receptors. CBD has a very low affinity for these receptors (100 fold less than THC) and when it binds it produces little to no effect. There is also growing evidence that CBD acts on other brain signaling systems, and that these actions may be important contributors to its therapeutic effects.

The Biology and Potential Therapeutic Effects of Cannabidiol

Doctor Reviewing MRI Scan, Credit: Stock Photography
Doctor Reviewing MRI Scan

The Study

Dr. Sagnik Bhattacharyya, reader of translational neuroscience and psychiatry at King’s College London and co-author, said in a statement: “The mainstay of current treatment for people with psychosis are drugs that were first discovered in the 1950s and unfortunately do not work for everyone. Our results have started unraveling the brain mechanisms of a new drug that works in a completely different way to traditional antipsychotics.”

In their small study, the researchers enlisted 33 young people who were experiencing psychotic symptoms, but had not yet been diagnosed with the condition, as well as 19 healthy participants who acted as a control. Of the participants enduring psychosis, 16 were given cannabis oil, while the remainder were assigned a placebo.

To document their brain, the participants were scanned with an MRI machine while they completed a memory task intended to use the parts of the brain associated with psychosis.

The results showed individuals dosed with cannabidiol had less severe abnormal brain activity than those assigned the placebo. That’s probably because cannabidiol switches brain activity to normal levels, the authors of the study believe.

Medical Marijuana: Cannabis Extract CBD Used To Successfully Treat Psychosis

Changing The Status Quo

For people suffering from psychosis or schizophrenia, CBD might just be a “game-changer”.

The impact of the substance has raised hopes that medical preparations of pure cannabidiol, or new drugs based on the compound, may be turned into effective treatments for young people who develop psychosis but do not respond to existing therapies.

The most common treatments for psychosis today work on a brain chemical called dopamine, but no new drugs have been developed for the condition since they were discovered in the 1950s.

Brain scans show how cannabis extract may help people with psychosis

Not only is CBD all-natural, non-addicting and non-psychoactive, but it’s also well tolerated too.

Significantly, the compound is very well tolerated, avoiding the adverse side effects such as weight gain and other metabolic problems associated with existing medicines.

“One of the reasons CBD is exciting is because it is very well tolerated compared to the other anti-psychotics we have available,” Bhattacharyya of King’s College said.

“There is an urgent need for a safe treatment for young people at risk of psychosis.”

Scientists unpick how cannabis component may fight psychosis

This recently published JAMA article highlights one more exciting therapeutic CBD use and we look forward to the upcoming results from their planned larger 300-patient clinical trial to test the true potential of CBD as a treatment; recruitment for the trial will begin in early 2019.

At TheraJoy, we are proudly a market leader in topical CBDTheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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